Thiamine disulfide

CAS No. 67-16-3

Thiamine disulfide( Algoneurina | Daiomin | TDS )

Catalog No. M27222 CAS No. 67-16-3

Thiamine, also known as thiamin or vitamin B1, is a vitamin found in food and manufactured as a dietary supplement and medication. Thiamine also acts as a cofactor for many centrally metabolizing enzymes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Thiamine disulfide
  • Note
    Research use only, not for human use.
  • Brief Description
    Thiamine, also known as thiamin or vitamin B1, is a vitamin found in food and manufactured as a dietary supplement and medication. Thiamine also acts as a cofactor for many centrally metabolizing enzymes.
  • Description
    Thiamine, also known as thiamin or vitamin B1, is a vitamin found in food and manufactured as a dietary supplement and medication. Thiamine also acts as a cofactor for many centrally metabolizing enzymes.
  • In Vitro
    Thiamine disulfide markedly inhibits production of progeny HIV-1 in acute and chronic HIV-1-infected CEM at nontoxic concentrations of 500-1000 μM. Thiamine disulfide (500 μM) blocks 99.7% of HIV-1 production after 96 hours culture in acute HIV-1 (LAV-1) infection, whereas it inhibits 90-98% of HIV-1 production in chronic-infected cells (CEM/LAV-1, H9/MN, and Molt-4/IIIB).
  • In Vivo
    ——
  • Synonyms
    Algoneurina | Daiomin | TDS
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    GRK5
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    67-16-3
  • Formula Weight
    562.71
  • Molecular Formula
    C24H34N8O4S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (444.28 mM)
  • SMILES
    C\C(N(Cc1cnc(C)nc1N)C=O)=C(\CCO)SS\C(CCO)=C(/C)N(Cc1cnc(C)nc1N)C=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Krause M, Foks H, Gobis K. Pharmacological Potential and Synthetic Approaches of Imidazo[4,5-b]pyridine and Imidazo[4,5-c]pyridine Derivatives. Molecules. 2017;22(3):399.
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